February 24, 2022

It’s well known that getting a good night’s sleep becomes more difficult as we age, but the underlying biology for why this happens has remained poorly understood.

A team of US scientists has now identified how the brain circuitry involved in regulating sleepfulness and wakefulness degrades over time in mice, which they say paves the way for better medicines in humans.

“More than half of people 65 and older complain about the quality of sleep,” Stanford University professor Luis de Lecea, who co-authored a study about the finding published Thursday in Science, told AFP.

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Source: Science of sleep: Why a good night’s rest gets harder with age